The Lagos government will shut the Oworonshoki-bound lane of the Third Mainland Bridge by midnight on Saturday, February 6.
The lane will not be reopened until 7pm on Sunday, February 7.
The temporary closure will enable construction workers remove the last expansion joint on the lane, transportation commissioner Frederic Oladeinde said in a statement on Wednesday.
The closure is vital to enable the contractor move its equipment to the Oworonshoki-bound lane within the given period without any interruption, he said.
Motorists from Ogudu, Alapere and Gbagada are advised to use Ikorodu Road, Jibowu and Yaba as alternative routes.
Iyana-Oworosoki-bound traffic from the Lagos Island, Iddo, Oyingbo, Adekunle and Yaba should use Herbert Macaulay Way, Jibowu and Ikorodu road as alternative routes.